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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HLTF
All Species:
18.18
Human Site:
Y13
Identified Species:
30.77
UniProt:
Q14527
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14527
NP_003062.2
1009
113929
Y13
K
R
D
P
V
W
K
Y
L
Q
T
V
Q
Y
G
Chimpanzee
Pan troglodytes
XP_001138277
1009
113822
Y13
K
R
D
P
V
W
K
Y
L
Q
T
V
Q
Y
G
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_534300
1106
124184
Y112
K
R
D
P
V
W
K
Y
L
Q
T
V
Q
Y
G
Cat
Felis silvestris
Mouse
Mus musculus
Q6PCN7
1003
113298
Y13
T
R
G
P
V
W
K
Y
S
Q
S
V
Q
Y
G
Rat
Rattus norvegicus
NP_001099948
974
110023
Y13
K
R
D
S
V
W
K
Y
S
Q
S
A
Q
Y
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508504
884
99044
V10
S
L
L
D
E
S
L
V
V
P
Y
G
A
N
N
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001090145
999
112576
F26
G
R
S
S
S
W
N
F
F
Q
L
A
Q
Y
G
Zebra Danio
Brachydanio rerio
XP_693071
942
104740
T13
S
S
T
A
S
S
S
T
P
P
R
Y
A
F
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P34739
1061
118357
S35
K
S
S
R
L
S
K
S
S
R
L
S
K
S
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786706
1093
121576
Q34
K
Q
T
P
N
K
K
Q
T
T
K
K
K
R
S
Poplar Tree
Populus trichocarpa
XP_002308876
799
88908
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FF61
881
98598
Baker's Yeast
Sacchar. cerevisiae
P31244
790
91412
Red Bread Mold
Neurospora crassa
Q7S1P9
1222
137173
D20
R
F
L
G
D
Q
G
D
S
D
H
V
A
G
G
Conservation
Percent
Protein Identity:
100
99.5
N.A.
85.5
N.A.
83.6
81.4
N.A.
71.7
N.A.
64.3
53.1
N.A.
21.1
N.A.
N.A.
34.5
Protein Similarity:
100
99.8
N.A.
88
N.A.
89.7
87.9
N.A.
78.5
N.A.
79.3
69.8
N.A.
41.2
N.A.
N.A.
53.1
P-Site Identity:
100
100
N.A.
100
N.A.
73.3
73.3
N.A.
0
N.A.
40
0
N.A.
13.3
N.A.
N.A.
20
P-Site Similarity:
100
100
N.A.
100
N.A.
80
80
N.A.
6.6
N.A.
46.6
6.6
N.A.
33.3
N.A.
N.A.
33.3
Percent
Protein Identity:
33.6
N.A.
N.A.
36
22.7
25.2
Protein Similarity:
50.4
N.A.
N.A.
52.7
40.9
43.9
P-Site Identity:
0
N.A.
N.A.
0
0
13.3
P-Site Similarity:
0
N.A.
N.A.
0
0
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
0
0
0
0
0
15
22
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
29
8
8
0
0
8
0
8
0
0
0
0
0
% D
% Glu:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
8
0
0
0
0
0
8
8
0
0
0
0
8
0
% F
% Gly:
8
0
8
8
0
0
8
0
0
0
0
8
0
8
50
% G
% His:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% I
% Lys:
43
0
0
0
0
8
50
0
0
0
8
8
15
0
0
% K
% Leu:
0
8
15
0
8
0
8
0
22
0
15
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
8
0
0
0
0
0
0
8
8
% N
% Pro:
0
0
0
36
0
0
0
0
8
15
0
0
0
0
0
% P
% Gln:
0
8
0
0
0
8
0
8
0
43
0
0
43
0
0
% Q
% Arg:
8
43
0
8
0
0
0
0
0
8
8
0
0
8
0
% R
% Ser:
15
15
15
15
15
22
8
8
29
0
15
8
0
8
15
% S
% Thr:
8
0
15
0
0
0
0
8
8
8
22
0
0
0
0
% T
% Val:
0
0
0
0
36
0
0
8
8
0
0
36
0
0
0
% V
% Trp:
0
0
0
0
0
43
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
36
0
0
8
8
0
43
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _